个人简介：

郭莹莹博士，医学院研究序列副教授。2018年博士毕业于哈尔滨工业大学。2018-2019年在中国农业科学院哈尔滨兽医研究所任副研究员。之后于2019年4月到西湖大学生命科学学院从事博士后研究工作。2022年4月加入体育竞彩官网,中国搜狗应用公司医学院鄢仁鸿课题组任研究副教授。博士和博士后期间一直从事重要病原与宿主的相互作用研究。在Nature、Science、Cell Research、Cell Discovery等杂志发表研究论文10篇。研究成果荣获2018年黑龙江省科学技术奖（自然）一等奖（第二完成人）；2020年浙江省自然科学奖一等奖（第四完成人）。

已发表文章列表：

1. Guo Y*, Zhang Y*, Yan R*, Huang B, Ye F, Wu L, Chi X, Shi Y, Zhou Q. Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states [J]. Nat Commun, 2022, 13(1): 3957.

2. Ma, H*., Guo, Y*., Tang, H*., Tseng, C.K., Wang, L., Zong, H., Wang, Z., He, Y., Chang, Y., Wang, S., et al. (2022). Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD. Cell Discov 8, 16..

3. Chi, X*., Guo, Y*., Zhang, G*., Sun, H., Zhang, J., Li, M., Chen, Z., Han, J., Zhang, Y., Zhang, X., et al. (2022). Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination. Signal Transduct Target Ther 7, 139.

4. Guo, Y*., Dong, L*., Qiu, X*., Wang, Y., Zhang, B., Liu, H., Yu, Y., Zang, Y., Yang, M., and Huang, Z. (2014). Structural basis for hijacking CBF-beta and CUL5 E3 ligase complex by HIV-1 Vif. Nature 505, 229-233.

5. Li, Y., Fan, Q., Zhou, B., Shen, Y., Zhang, Y., Cheng, L., Qi, F., Song, S., Guo, Y., Yan, R., et al. (2022). Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants. iScience, 104431.

6. Yan, R., Zhang, Y., Li, Y., Ye, F., Guo, Y., Xia, L., Zhong, X., Chi, X., and Zhou, Q. (2021). Structural basis for the different states of the spike protein of SARS-CoV-2 in complex with ACE2. Cell Res 31, 717-719.

7. Yan, R., R. Wang, B. Ju, J. Yu, Y. Zhang, N. Liu, J. Wang, Q. Zhang, P. Chen, B. Zhou, Y. Li, Y. Shen, S. Zhang, L. Tian, Guo, Y., L. Xia, X. Zhong, L. Cheng, X. Ge, J. Zhao, H. W. Wang, X. Wang, Z. Zhang, L. Zhang and Q. Zhou. (2021). Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies. Cell Res 31, 517-525.

8. Yan, R., Zhang, Y., Li, Y., Xia, L., Guo, Y., and Zhou, Q. (2020). Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2. Science 367, 1444-1448.

9. Chi, X., R. Yan, J. Zhang, G. Zhang, Y. Zhang, M. Hao, Z. Zhang, P. Fan, Y. Dong, Y. Yang, Z. Chen, Y. Guo, J. Zhang, Y. Li, X. Song, Y. Chen, L. Xia, L. Fu, L. Hou, J. Xu, C. Yu, J. Li, Q. Zhou and W. Chen. (2020). A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2. Science 369, 650-655.

10. Hou, Y., Guo, Y., Wu, C., Shen, N., Jiang, Y., and Wang, J. (2012). Prediction and identification of T cell epitopes in the H5N1 influenza virus nucleoprotein in chicken. PLoS One 7, e39344.